The meaning of MAIN is physical strength : force —used in the phrase with might and main. How to use main in a sentence.

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The main thing is to keep calm and don’t get angry. The main social event of the summer was a dance and reception.

chief in size, extent, importance, etc.; principal; leading; specif., designating a large central unit on which subsidiaries or branches depend the main post office

main (meɪn) adj (prenominal) 1. chief or principal in rank, importance, size, etc 2. sheer or utmost (esp in the phrase by main force)

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physical strength, power, or force: to struggle with might and main. the chief or principal part or point: The main of their investments was lost during the war.

MAIN definition: chief in size, extent, or importance; principal; leading. See examples of main used in a sentence.

Synonyms for MAIN: primary, greatest, predominant, highest, dominant, foremost, big, first; Antonyms of MAIN: last, least, minor, secondary, slight, unimportant, trivial, insignificant